Salicylates Inhibit Flavivirus Replication Independently of Blocking Nuclear Factor Kappa B Activation
نویسندگان
چکیده
منابع مشابه
Salicylates inhibit flavivirus replication independently of blocking nuclear factor kappa B activation.
Flaviviruses comprise a positive-sense RNA genome that replicates exclusively in the cytoplasm of infected cells. Whether flaviviruses require an activated nuclear factor(s) to complete their life cycle and trigger apoptosis in infected cells remains elusive. Flavivirus infections quickly activate nuclear factor kappa B (NF-kappaB), and salicylates have been shown to inhibit NF-kappaB activatio...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2001
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.75.17.7828-7839.2001